UPDATED January 20,2017 – Congestive Heart Failure or CHF is a state wherein the heart does not have the capability to properly function as a pump. As a result of the cardiac-malfunction the oxygen pumped into the body is insufficient. Congestive heart failure is generally caused by simultaneous illnesses.  Illnesses that weaken the cardiovascular system, heart muscle,or diseases that trigger the heart muscles to become stiff, or illnesses that create an increase in oxygen demands for the body which consequently increases the supply for fresh oxygen by the body when the heart is incapable of producing oxygen-rich blood at the level needed.

Congestive heart failure and ishchemic heart disease can have an impact on numerous organs in the body. For instance, the injured areas of the heart directly affected by the sickness does not have the capability to produce enough blood for the kidneys, which then affect their capability to excrete water and salt (sodium). The distressed kidney function may cause the body to retain more fluids than needed by the body. The lungs also may develop pulmonary edema (PE).

Stem Cell Treatment for Heart Failure

Cardiac tissue regeneration using clinical grade mesenchymal stem cells. Regenerated heart tissue and creation of new blood vessels leads to improvement in overall cardiac function and reduction in the infarct zone without adverse side effects.

PE occurs when the fluid in the lungs diminishes a person’s ability to exercise normally. Fluid might likewise accumulate inside the liver, which directly affects it function by impairing the livers capability to create important proteins and also in helping clear the body of harmful elements and/or toxins. The intestines might also turn out to be much less effective in being able to absorb the vitamins, nutrients and medicines a human needs. The fluids in the body can also accumulate quickly which could result to edema (severe swelling) of the ankles and feet.

How Does Stem Cell Treatment for CHF Work?

An Ejection fraction of 20% would be considered a dangerous level and therefore indicates a highly advanced stage of heart failure. Healthy people without any cardiovascular diseases usually have ejection fractions in between 52% and 68%.

The primary issue is the fact that the chamber responsible for pumping one’s heart (The left ventricle) becomes enlarged and isn’t beating effectively causing   the EF percentage level to dangerously low levels. Ideally, EF percentages ought to be between 52% and 74%. This number also represents the quantity of blood pumped out from the heart on every beat. The walls of the left ventricle are hypokinetic. Hypokenetic state indicates they are not contracting correctly, they’re considered “lazy”. This is also why the EF% is low and the patients have Diastolic Dysfunction of the heart.

Recent Patient Who Received Cardiac Cells to Repair Heart Failure

Cell Therapy for Congestive Heart Failure

Stem cells are un-specialized cells that have two essential characteristics that distinguish them from other cells inside our bodies. Stem Cells are able to replenish their numbers naturally and indefinitely via cell division. If stem cells ever receive chemical indicators (ie dysfunctions, trauma,damage etc) they are able to migrate to the injured/dysfunctional area and transform themselves into the very specialized cells needed to perform a particular functions. Functions or tissues or cells like nerve cells or even heart cells. Other cardiovascular treatments include:

• Stem cell therapy for Coronary artery disease

• Stem cell therapy for Angina

• Stem cell therapy for Heart disease

• Stem cell therapy for Cardiomyopathy

• Stem cell therapy for Ischemia

• Stem cell therapy for Heart Attacks

Cardiac Regeneration Therapy – Overview

Once qualified for treatments,Injections of enriched mesenchymal stem cells are introduced into damaged heart tissue. This cellular proliferation helps enhance the performance/condition patients suffering from serious congestive heart failure. Stem cells for CHF works primarily through the creation of new blood vessels “Angiogenesis” that also helps improve tissue perfusion. The newly lab grown/expanded cells are carefully “transplanted” back into the patient through targeted infusions and/or into the damaged heart muscle or even by infusing them into the coronary arteries. Through the process of “Homing” (Suárez-Álvarez, López-Vázquez, and López-Larrea 2012)* Stem cells migrate into the heart muscle for months after the initial treatment to assist in the regeneration process through the transformation into healthy functioning heart cells.

Benefits of having CHF Cell Therapy:

• Sustained improvement in heart pumping power and its ability to regulate proper supply blood to the body (Oguz et al. 2011)*

• Improved regulation of O2 (Oxygen) Intake and Use  (Sheng, Zhou, and Hao 2012)*

• Greater Reduction in Angina (Hou et al. 2013)*

• Reduction in the infarct size with Reduction in heart muscle scar

• Noticeable improvement in the patients overall well-being and physical endurance.

TREATMENT PRECAUTION

Please note Stem Cell Therapies may not be appropriate for all Heart Conditions. Cell Therapy and Heart tissue and cell Engineering are limited based on the extent of heart muscle and tissue damage and current and accurate medical condition of the patient. Travel Restrictions may apply. Patients requiring sustained oxygen assistance will not qualify for the treatment.

Treatment Overview


Number of Stem Cell Injections for CHF: 2-6 Clinical Grade Cell Injections of Hematopoietic Mesenchymal Stem cells (per Treatment stage requirement) Severe cases with multiple comorbidities may require a multiple stage delivery using transvascular injections with direct injection Into the ventricular walls to ensure optimal results.

Physical Rehabilitation Treatment for CHF: Rehabilitation therapy is optional based on the patients time constraints. Full rehabilitation and nursing care can be provided 2-4 hours per day and up to 4 days per week
. Medical visas and accommodations for the patient and family/friends at an extended stay hotel can also be included upon request. Estimated treatment length is 14 – 21 nights in total.

Cost for Treating Congestive Heart Failure