UPDATED January 19,2017 – According to international statistics, chronic liver disease ranks #4 around the world as the top causes of mortality.  Once a human liver incurrs serious damage, it usually cannot repair itself naturally thus may posing life-threatening risks to the patient. Given this, the only possible treatment options for chronic liver disease was with a dangerous complete liver transplant. Unfortunately there are a lot of risks to consider with liver transplant surgery. The risk is mainly attributed to the tendency of rejection of a transplanted organs. Sometime the body detects the transplanted organ as a “foreign object”, or something that has not come from its own body therefore should be destroyed/rejected.

Treat Liver Damage & Failure With Stem Cells

Organ donors are very limited and the prices for liver transplants is very high and the surgery itself involves many risks. Thankfully, our Internationally trained stem cell regeneration doctors were able to create a more modern approach to healing. Adult stem cell therapies help induce the rapid production of hepatocytes in a patient with chronic liver disease and/or Cirrhosis of the Liver.

Common Causes of Liver Cirrhosis

Some of the most common causes of chronic liver disease in men and women are attributed:

• Alcoholism and Alcoholic cirrhosis

• Eating too much fatty foods

• Hypertension

• Fatty Liver

• Hepatitis C

• Primary biliary cirrhosis (PBC)

As you may notice, most of the common causes of chronic liver disease are modifiable before they become an issue by altering your eating and health habits. The best treatment plans always start with prevention.  Healthy living practices are crucial if you want  to avoid chronic liver disease.

The Liver is the largest organ in the human body and is fully capable of regenerating itself under normal conditions. Since the Liver has many responsibilities  such as detoxification of the blood, fighting infections and aiding in the digestion of foods, it can be severely impact the overall health of a person if it becomes diseased.

Treatment for Cirrhosis of Liver & Fibrosis

Enhanced mesenchymal stem cells (MSCs) offer an attractive therapeutic solution to treat liver diseases based on many factors including:

• Immunomodulatory properties (Zimmermann and McDevitt 2013)*

• Ability to differentiate into hepatocytes

• Natural replacement of damaged hepatocyte cells

• Promote persistent hepatocyte regeneration

• Capacity to inhibit cell activation

• Increases rate of apoptosis ( paracrine mechanism )

With recent advancements in regenerative medicine such as stem cell therapy for Kidney and Liver disease, there is finally the possibility of safely treating chronic liver disease through a targeted organ regeneration protocol of cell transplants.

Our stem cell treatment protocol for liver disease can also be done by using induced pluripotent stem cells. Pluripotent and Multipotent stem cells are capable of differentiating into different kinds of cells including hepatocytes (liver cells).

The liver is generally made up of cells called hepatocytes (Allameh and Kazemnejad 2012)*. These liver cells are capable of replicating so that new hepatocytes will be replacing old hepatocytes naturally after 200 to 300 days of use. If a patient’s liver is severely damage, the natural replicating process cannot be completed by the hepatocytes. This is where oval cells come to the rescue. It is believed that oval cells are also capable of producing new hepatocytes should the need arise. Our Non-Invasive treatment for Liver Disease looks to introduce therapeutic levels of  hepatocytes liver cells and/or Hepatic oval cells to forcefully assist in the healing of damaged tissues and cells.(Ming Shi et al. 2012)*

TREATMENT PRECAUTION

Patients with severe liver functions,multiple conditions or Advanced stages with travel limitations will not qualify for the 2-3 week treatment. Please contact us for medical review.

Treatment for Cirrhosis using Hepatocyte Cell Transplants

Computed Tomography Angiography or CTA is often used for delivery of stem cells to a very precise method of hepatocytes or oval cell delivery using a catheter. The femoral catheter used can be guided to appropriate areas of damage (Esrefoglu 2013)*. The damaged tissues/livers being treated requires about 90 minutes in total per treatment at our regeneration center.

Therapy for Fatty Liver Disease, Liver Fibrosis and Liver Cirrhosis

Total Cell Infusions for Liver Cirrhosis: 2-6 Enriched Hepatocyte cell Infusions per treatment stage. Severe cases may require several stages.

Type of Cells and Delivery Method: 
Liver regeneration therapy using enriched Hepatocyte cells. Autologous cell therapy using PBSC ‘Peripheral Blood’ or marrow derived stem cells. For older patients or patients with severe or multiple conditions, a more aggressive treatment plan may be needed using allogeneic stem cells derived from Cord blood, Amniotic Membrane or enriched Placenta cells . Our cell transplants do not require invasive surgery. Cells are delivered through the combination of IV Drips (Intravenous),Direct injection and/or Intrathecal Injections.