深圳市瑞普逊干细胞再生医学研究院

Shenzhen Ruipuxun Academy  for Stem Cell & Regenerative Medicine

Alzheimers

Neural Stem Cell Treatment for Alzheimers & Dementia Brain Disease

UPDATED January 19, 2017 Alzheimer’s is also known in medical literature as Alzheimer’s Disease (AD) is the most common type of dementia. As of Today, there are no effective pharmaceutical based therapies for the illness.

The condition is terminal and if left untreated will eventually lead to death. AD is usually being diagnosed in old people, aged sixty five years plus, but of course, it can also occur in an earlier age.In 2007, there were an estimated 33.5 million people suffering from AD throughout the world. Alzheimer’s is said to affect one in every eighty individuals globally by 2040.(Fitzsimons et al. 2014)*

Signs & Symptoms of Alzheimers & Dementia

Dementia and Alzheimers show a wide variety of symptoms including personality changes, memory loss followed by severely impaired intellectual/cognitive functions that arise from the disease itself or from any trauma to the brain. Such symptoms are NOT part of the normal aging cycle and are usually severe enough to impact the daily activities, relationships and independence of the affected persons. Alzheimer’s “AD” is the most common known type of dementia, but there are other diagnosed forms of the neurodegenerative disease including vascular dementia and mixed dementia.

Patients with dementia, usually have a rapid decline in memory function, learning, communication and solving simple problems. For some, these changes take several years to occur but for many, the neurological function deteriorates very quickly and if left untreated, will not be reversible.

The rate of progression and eventual outcome of AD and dementia vary patient to patient, but is usually determined by the area of the brain that is effected and the type of dementia which they are diagnosed with. Early diagnosis and treatment are the patients best hope. Thanks to modern tests for the disease, early detection is quite simple using advanced brain imaging such as CT Scans, MRI’s, clinical examinations from neurologists and other diagnostic tests.

Common symptoms & signs or AD and dementia:

  • Loss of communication skills

  • Rapid Memory loss

  • Motor Function,Gait and balance issues

  • Difficulty making decisions

  • Difficulty with abstract thoughts

  • Faulty reasoning

  • Inappropriate verbal and physical behavior

  • Impaired judgment

  • Autonomic neuropathy

  • Disorientation of time and location

  • Paranoia, frequent agitation or Hallucinations

  • Complete neglect of personal hygiene and safety

People with Dementia and Alzheimer’s might also:

  • Asks the same question repeatedly

  • Cannot recognize family or friends

  • Unable to remember or follow directions

  • Become lost or disoriented in very familiar places

 Stem Cell Treatment for Alzheimer’s ( VIDEO )

Alzheimer’s disease affects each individual in a distinct way, there are still the usual indicators that one is suffering from the disease. Early warning signs are more usually misconceived to be normal aging process or just manifestations of stress and depression. In the early stage, the most common signs you can observe are difficulty in remembering current happenings. Potential Parkinson’s Disease and AD patients, can be diagnosed and verified through examinations that gauge behavior and thinking abilities, followed with an more thorough examination of the brain or a CT brain scan. As the diseases becomes more apparent, the warning signs can include being frustrated easily, irritated easily, becoming much more hostile, wild mood swings, difficulty in speech, language and the long-term loss of memory. As the patient becomes more and more affected, they usually begin to isolate themselves from their family and the community. The body is affected gradually, and unfortunately, this leads to death.

The disease affects each person distinctively. Consequently, this makes it harder to predict how it will play out. AD could worsen without the patient’s knowledge and be left undiscovered for a long time. The usual lifespan for people diagnosed with Alzheimer’s is roughly three to seven years. Less than three percent of patients can live up to fourteen years or longer after being diagnosed with AD.(Liu et al. 2013)*

Alzheimers-dementia-comparison-normal-brain

This is exactly where adult stem cell treatment for Alzheimer’s comes into the picture. The Regeneration Center of Thailand offers a unique and effective treatment plan to help patients recover by replenishing damaged/lost neuronal connection/signal systems. The  cells are introduced in the damaged regions from the human brain where they proliferate and matured to functional neurons. Sensory precursor cells can be intravenously dealt with but it can also be directly implanted into the brain-damaged locations and bring about recovery of the patient. There is also substantial proof that transplanted stem cells or the neural precursor cells (NPCs) can survive, stir and gradually develop into neurons, oligodendrocytes and astrocytes. Stem cells, in addition to replacement of lost and/or damaged cells, can also induce endogenous neural precursors, help boost the structural neuroplasticity, and regulate pro-inflammatory cytokines and the neuronal apoptotic death.(Blurton-Jones et al. 2014)*

cell-comparison-neural

How Neural Cell Replacement Therapy Works

In order to push growth elements into the brain, stem cells can also be genetically modified. Studies indicate that the full-grown brain of the mammals preserves the capability to produce new neurons from the neural stem or progenitor cells. Stem cell therapy is one of the most practical and effective way to repair the damages brought about by Brain Injuries, Strokes, Alzheimer’s and of course, to recover intellectual function and quality of life for the patient and family affected by the disease.(Khairallah et al. 2014)*

2017年6月21日 18:19
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